DAIDS Adverse Event Grading Tables

The Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events consists of parameters, or Adverse Events (AEs), with severity grading guidance that are to be used in DAIDS clinical trials for safety data reporting to maintain accuracy and consistency in the evaluation of AEs.

Below are the Grading Tables (Versions 1.0, 2.0 and 2.1), ​suggested citations, applicable clarification documents, and additional resources. The protocol will specify which DAIDS Adverse Event Grading Table is applicable.

DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 2.1

Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events Version 2.1 - March 2017

• Suggested Citation 
  U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 2.1. [March 2017]. Available from:
  https://rsc.tech-res.com/docs/default-source/safety/daids-ae-grading-table-mar2017.pdf


• Clarification Documents for the DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events 
  Version 2.1 - March 2017
  

  	Grading Table with all Changes Highlighted
  	Parameter Level Summary of Changes

DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 2.0

Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events Version 2.0 - November 2014

• Suggested Citation 
  U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 2.0. [November 2014]. Available from:
  http://rsc.tech-res.com/docs/default-source/safety/daids_ae_grading_table_v2_nov2014.pdf


• Clarification Documents for the DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events 
  Version 2.0 - November 2014
  

  	Grading Table with all Changes Highlighted
  	High Level Summary of Changes
  	Parameter Level Summary of Changes

DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 1.0

Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events Version 1.0 - December 2004 (Clarification dated August 2009)

• Suggested Citation 
  U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 1.0. [Updated August 2009]. Available from: http://rsc.tech-res.com/docs/default-source/safety/table_for_grading_severity_of_adult_pediatric_adverse_events.pdf

Memo Regarding the Clarification to the Table for Grading Severity of Adult and Pediatric Adverse Events

Additional Grading Table Resources

	Addendum 1 – Female Genital Grading Table for Use in Microbicide Studies Version 1.0 – November 2007
	Addendum 2 – Male Genital Grading Table for Use in Microbicide Studies Version 1.0 – November 2007
	Addendum 3 – Rectal Grading Table for Use in Microbicide Studies (Clarification dated May 2012) Version 1.0 – November 2007 (Clarification dated May 2012)
	Memo Regarding the Clarification to the Rectal Grading Table for Use in Microbicide Studies

​Previous versions are available upon request at DAIDSRSCSafetyOffice@tech-res.com.